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First Look: Jessica Chastain, Josh O’Connor, Paul Mescal, More Appear On “Tonight Show Starring Jimmy Fallon”

“Fallon” is back with an absolutely loaded lineup.

THE TONIGHT SHOW STARRING JIMMY FALLON -- Episode 2176 -- Pictured: (l-r) Actors Josh O'Connor & Paul Mescal during an interview with host Jimmy Fallon on Tuesday, September 2, 2025 -- (Photo by: Todd Owyoung/NBC)

“The Tonight Show Starring Jimmy Fallon” returns from summer hiatus with a bang, showcasing four interview guests and a high-profile musical collaboration.

Airing Tuesday, the episode welcomes Jessica Chastain as its lead interview guest. Josh O’Connor and Paul Mescal also appear for a joint interview, and Sabrina Impacciatore additionally drops by for a chat.

After the interviews, the NBC talk show offers a stage for Carlos Vives, Arthur Hanlon, and Goyo to deliver a musical performance.

Filmed in advance, the episode will air at 11:35PM ET/PT on NBC. First-look photos follow:

THE TONIGHT SHOW STARRING JIMMY FALLON — Episode 2176 — Pictured: (l-r) Actress Jessica Chastain during an interview with host Jimmy Fallon on Tuesday, September 2, 2025 — (Photo by: Todd Owyoung/NBC)
THE TONIGHT SHOW STARRING JIMMY FALLON — Episode 2176 — Pictured: (l-r) Actress Sabrina Impacciatore during an interview with host Jimmy Fallon on Tuesday, September 2, 2025 — (Photo by: Todd Owyoung/NBC)
THE TONIGHT SHOW STARRING JIMMY FALLON — Episode 2176 — Pictured: (l-r) Musical guests Carlos Vives, Arthur Hanlon, and Goyo perform together on Tuesday, September 2, 2025 — (Photo by: Todd Owyoung/NBC)
THE TONIGHT SHOW STARRING JIMMY FALLON — Episode 2176 — Pictured: (l-r) Actors Josh O’Connor & Paul Mescal during an interview with host Jimmy Fallon on Tuesday, September 2, 2025 — (Photo by: Todd Owyoung/NBC)
THE TONIGHT SHOW STARRING JIMMY FALLON — Episode 2176 — Pictured: (l-r) Actors Josh O’Connor & Paul Mescal during an interview with host Jimmy Fallon on Tuesday, September 2, 2025 — (Photo by: Todd Owyoung/NBC)

Written by Brian Cantor

Brian Cantor is the editor-in-chief for Headline Planet. He has been a leading reporter in the music, movie, television and sporting spaces since 2002.

Brian's reporting has been cited by major websites like BuzzFeed, Billboard, the New Yorker and The Fader -- and shared by celebrities like Taylor Swift, Justin Bieber and Nicki Minaj.

Contact Brian at brian.cantor[at]headlineplanet.com.

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